发明名称 |
UJI DIAGNOSTIK TUBERKULOSIS |
摘要 |
A method of diagnosing in a host infection by or exposure to a mycobacterium which expresses ESAT-6 comprising (i) contacting a population of T cells from the host with one or more peptides or analogues selected from the peptides represented by SEQ ID NO:1 to 11 and analogues thereof which can bind a T cell receptor which recognises any of the said peptides, and (ii) determining whether the T cells of said T cell population recognise the peptide(s) and/or analogue(s). The method may performed in vivo. Peptides and a kit which enable the method to be carried out are provided. |
申请公布号 |
ID29858(A) |
申请公布日期 |
2001.10.18 |
申请号 |
ID20010000974 |
申请日期 |
1999.11.03 |
申请人 |
ISIS INNOVATION LIMITED |
发明人 |
AJIT LALVANI;ANSAR A. PATHAN |
分类号 |
G01N33/53;A61K38/00;A61K48/00;A61K49/00;C07K14/35;C12N15/09;C12Q1/02;C12R1/32;G01N33/569;(IPC1-7):C07K14/35;C07K7/08;C07K16/12;C12Q1/68;A61K31/70;A61K38/10;G01N33/68 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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