发明名称 Prostaglandin receptor ligands
摘要 Compounds and methods for treating prostaglandin mediated diseases, and certain pharmaceutical compositions thereof are disclosed. The compounds are represented by formula II: <paragraph lvl="0"><in-line-formula>Ar1-W-Ar2-X-Q II </in-line-formula>The compounds of the invention are structurally different from NSAIDs and opiates, and are antagonists of the pain and inflammatory effects of E-type prostaglandins.
申请公布号 US2001031766(A1) 申请公布日期 2001.10.18
申请号 US20010781385 申请日期 2001.02.12
申请人 MERCK FROSST CANADA & CO. 发明人 BELLEY MICHEL;LACHANCE NICHOLAS;LABELLE MARC;GALLANT MICHEL;CHAURET NATHALIE;TRIMBLE LAIRD A.
分类号 A61K31/18;A61K31/185;A61K31/192;A61K31/357;A61K31/36;A61K31/381;A61K31/41;A61K31/433;A61K31/4704;A61K45/00;A61P1/02;A61P11/06;A61P15/06;A61P17/02;A61P19/02;A61P19/04;A61P19/06;A61P25/28;A61P27/06;A61P29/00;A61P35/00;A61P37/00;A61P43/00;C07C59/52;C07C59/64;C07C59/66;C07C59/68;C07C59/90;C07C62/34;C07C309/10;C07C311/51;C07C323/60;C07C323/62;C07D215/18;C07D215/36;C07D257/04;C07D285/12;C07D285/135;C07D307/79;C07D317/60;C07D333/28;C07D333/34;(IPC1-7):A61K31/47;A61K31/404;A61K31/403 主分类号 A61K31/18
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