发明名称 |
AN ENGINEERED RECOMBINANT MOLECULE THAT REGULATES HUMORAL AND CELLULAR EFFECTOR FUNCTIONS OF THE IMMUNE SYSTEM |
摘要 |
Recombinant chimeric molecules that include at least a domain capable of regulating the humoral effector functions of the immune system and another domain capable of regulating the cellular effector functions of the immune system are provided. Recombinant DNA constructs having DNA sequences encoding the above mentioned chimeric proteins are provided. Cloning vectors incorporating the above DNA constructs and cells transformed with the vectors and host cells containing such vectors are also provided. Transgenic cells, tissues, organs, and animals incorporating the above-mentioned chimeric molecules are provided.
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申请公布号 |
WO0130966(A3) |
申请公布日期 |
2001.10.18 |
申请号 |
WO2000US29151 |
申请日期 |
2000.10.21 |
申请人 |
ALEXION PHARMACEUTICALS, INC.;FODOR, WILLIAM, L.;PIZZOLATO, MARYELLEN |
发明人 |
FODOR, WILLIAM, L.;PIZZOLATO, MARYELLEN |
分类号 |
C07K14/705;(IPC1-7):C12N5/00;C12N15/00;C12N15/09;C12N15/63;C07K1/00;C07K14/00;C07K17/00 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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