发明名称 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE
摘要 The present invention is directed to peptidomimetic compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.
申请公布号 WO0176694(A1) 申请公布日期 2001.10.18
申请号 WO2001US11395 申请日期 2001.04.06
申请人 MERCK & CO., INC.;STUMP, CRAIG, A.;WILLIAMS, THERESA, M. 发明人 STUMP, CRAIG, A.;WILLIAMS, THERESA, M.
分类号 A61K31/335;A61K41/00;A61K45/06;A61P27/00;C07D487/04;C07D498/04;C07D513/04;(IPC1-7):A61P27/00;A61K31/425;A61K31/54;A61K31/42;A61K31/535;A61K31/415;A61K31/44;C07D279/04;C07D279/06;C07D417/00;C07D498/02;C07D471/02;C07D513/02;C07D235/02 主分类号 A61K31/335
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