| 发明名称 |
Mixed buffer system for stabilizing polypeptide formulations |
| 摘要 |
The present invention is a pharmaceutical composition for polypeptdes which are not stably soluble. A preferred polypeptide is monomeric insulin and a preferred formulation consists of a TRIS-phosphate combination buffer, zinc; a phenolic preservative and an isotonicity agent such as glycerol.
|
| 申请公布号 |
US2001031726(A1) |
申请公布日期 |
2001.10.18 |
| 申请号 |
US20000733738 |
申请日期 |
2000.12.08 |
| 申请人 |
MINIMED, INC. |
发明人 |
VAN ANTWERP WILLIAM PETER;GULATI POONAM S. |
| 分类号 |
A61K38/28;A61K47/02;A61K47/12;A61K47/18;A61P3/10;(IPC1-7):A61K38/28 |
主分类号 |
A61K38/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
