发明名称 |
VERFAHREN ZUR HERSTELLUNG VON 3-NORCEPHEM-VERBINDUNGEN |
摘要 |
<p>The present invention provides a process for preparing 3-norcephem compound represented by the formula (2), characterized in that a hydride reagent is acted on a halogenated beta -lactam compound represented by the formula (1) in the presence of a cuprous compound <CHEM> wherein R1 is a hydrogen atom, amino group or protected amino group, R2 is an aryl or substituted aryl, n is 0 to 2, R3 is a hydrogen atom or carboxylic acid protective group, X is a halogen atom, and Y is a halogen atom or a leaving group <CHEM> wherein R1 and R3 are as defined above.r</p> |
申请公布号 |
DE69706632(D1) |
申请公布日期 |
2001.10.18 |
申请号 |
DE1997606632 |
申请日期 |
1997.06.09 |
申请人 |
OTSUKA KAGAKU KABUSHIKI KAISHA, OSAKA |
发明人 |
SASAOKA, M.- O. K. K. KAISHA TOKUSHIMA LABORA;TORII, SIGERU;TANAKA, HIDEO;KIKUCHI, R.-OTSUKA K. K. KAISHA TOKUSHIMA LAB;KAMEYAMA, Y. - OTSUKA K. K. KAISHA TOKUSHIMA L |
分类号 |
C07D501/00;C07D501/08;C07D501/16;C07D501/20;C07D501/22;(IPC1-7):C07D501/08 |
主分类号 |
C07D501/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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