| 发明名称 |
POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED 4-PYRONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE |
| 摘要 |
The invention relates to polycyclic aryl and heteroaryl substituted 4-pyrone compounds useful as inhibitors of serine proteases of the coagulation cascad e and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
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| 申请公布号 |
CA2405561(A1) |
申请公布日期 |
2001.10.18 |
| 申请号 |
CA20012405561 |
申请日期 |
2001.04.04 |
| 申请人 |
PHARMACIA CORPORATION |
发明人 |
NEUMANN, WILLIAM L.;SOUTH, MICHAEL S.;RAHMAN, HAYAT K.;KOELLER, KEVIN J.;MA, CHUN C. |
| 分类号 |
A61K31/351;A61P7/02;A61P9/10;A61P43/00;C07D309/38;C07D309/40;C07D405/12;(IPC1-7):C07D309/38 |
主分类号 |
A61K31/351 |
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