21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) and its use as medicament for treating excess of glucocorticoids

摘要

The comformationally highly bent steroid 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) has been found to be a selective antiglucocoriticoid virtually lacking mineralococorticoid or glucocorticoid properties as well as affinity for MR or PR and is used for the treating of diseases associated with an excess of glucocordcoids in the body, such as the Cushing's syndrome or depression.