发明名称 |
Anti-microbial-adhesion fraction derived from vaccinium |
摘要 |
A non-food anti-microbial-adhesion and aggregation composition comprising a suitable carrier and an effective amount of an adhesion inhibitory fraction isolated from juice from berries of the Vaccinium plant genus. In an embodiment the anti-aggregation and adhesion fraction is isolated from cranberry juice. It is characterized as being polymeric and having a molecular weight >=14,000; an elemental analysis of carbon 43-51%, hydrogen 4-5%, no nitrogen, no sulfur and no chlorine; a nuclear magnetic resonance (NMR) line spectrum as set forth in FIGS. 2A and 2B; and an ultraviolet spectrum with an absorption peak at 280 nm in neutral or acidic pH solution which is absent in alkali solutions. This fraction exhibits adhesion inhibitory activity against P fimbriated bacteria, oral bacteria and Helicobacter pylori.
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申请公布号 |
US6303125(B1) |
申请公布日期 |
2001.10.16 |
申请号 |
US19980159626 |
申请日期 |
1998.09.24 |
申请人 |
RAMOT-UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. |
发明人 |
OFEK ITZHAK;WEISS ERVIN;KASHMAN YOEL;GOLDHAR JANINA;SHARON NATHAN |
分类号 |
A01N25/02;A23L1/30;A23L2/02;A23L2/56;A61K;A61K8/97;A61K31/00;A61K36/45;A61P31/04;A61Q11/00;(IPC1-7):A01N65/00 |
主分类号 |
A01N25/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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