发明名称 |
Purification of fermented clavulanic acid |
摘要 |
A process for the production of clavulanic acid and pharmaceutically acceptable salts thereof by a) fermentation of a micro-organism which is capable to produce clavulanic acid b) isolation of clavulanic acid from the fermentation broth c) purification of clavulanic acid, e.g. via a salt thereof d) conversion of the purified clavulanic acid of step c), e.g. of a salt thereof into a pharmaceutically acceptable salt of clavulanic acid, wherein the fermentation broth is extracted with a solvent prior to isolation of clavulanic acid.
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申请公布号 |
US2001029038(A1) |
申请公布日期 |
2001.10.11 |
申请号 |
US20010871357 |
申请日期 |
2001.05.31 |
申请人 |
SUMMER HARALD;RENZL ALOIS;WAGNER HELMUT |
发明人 |
SUMMER HARALD;RENZL ALOIS;WAGNER HELMUT |
分类号 |
C07D503/00;(IPC1-7):C12P17/18 |
主分类号 |
C07D503/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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