发明名称 |
METHODS AND COMPOSITIONS FOR USE OF CATALASE IN HYDROGELS AND BIOSENSORS |
摘要 |
Hydrogels containing catalase co-immobilized with an analyte-sensitive enzyme such as glucose oxidase are disclosed. The hydrogels may be pH-sensitive, and preferably are thin and lightly crosslinked. The catalase is present in concentrations ranging generally from 100 units/ml to about 1000 units/ml. These hydrogels have much faster swelling response times as compared to hydrogels without catalase, and are useful in biosensors and analyte-responsive drug delivery devices. The hydrogels also have an increased useful life, due to protection of the immobilized analyte-sensitive enzyme from degradation by hydrogen peroxide.
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申请公布号 |
WO0175089(A1) |
申请公布日期 |
2001.10.11 |
申请号 |
WO2001US10612 |
申请日期 |
2001.04.02 |
申请人 |
M-BIOTECH, INC. |
发明人 |
IN SUK, HAN;DAL-YOUNG, JUNG |
分类号 |
C12N11/18;(IPC1-7):C12N11/18;C12M1/34;C12M1/40;C12N11/02;C12N11/04;C12N11/08 |
主分类号 |
C12N11/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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