发明名称 |
PENGOBATAN KOMBINASI DARI PENGHAMBAT ENZIM PENGUBAH ANGIOTENSI DAN ANTAGONIS ALDOSTERON UNTUK MENURUNKAN MORBIDITAS DAN MORTALITAS DARI PENYAKIT KARDIOVASKULER |
摘要 |
Combinations of an ACE inhibitor, an aldosterone antagonist, and a loop diuretic are described for use in treatment of circulatory disorders. Of particular interest are therapies using captopril, enalapril or lisinopril co-administered with spironolactone. This co-therapy would be particularly useful to reduce the death rate or the number of non-fatal hospitalizations or prevent the progression of congestive heart failure in patients with cardiovascular disease. |
申请公布号 |
ID29778(A) |
申请公布日期 |
2001.10.11 |
申请号 |
ID20010000977 |
申请日期 |
1999.11.05 |
申请人 |
G.D. SEARLE & CO. |
发明人 |
ALFONSO T. PEREZ;RICHARD J. LACHAPELLE;BARBARA RONIKER;DEBRA J. ASNER;JOHN C. ALEXANDER |
分类号 |
A61K31/341;A61K31/401;A61K31/585;A61K31/7048;A61K38/55;A61K45/06;A61P9/00;A61P9/04;A61P9/12 |
主分类号 |
A61K31/341 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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