发明名称 SUBSTITUTED 2-THIO-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND THE USE THEREOF AS ADENOSINE RECEPTOR LIGANDS
摘要 The invention relates to compounds of general formula (I), a method for the production thereof and the use thereof as pharmacologically effective substances for a broad medical indication spectrum. Furthermore, selective adenosine receptor ligands, preferably selective adenosine A1-, adenosine A2a- and/or adenosine A2b-receptor ligands are provided for the prophylaxis and/or the treatment of diseases, especially cardiovascular diseases, diseases of the urogenital region, diseases of the respiratory tract, inflammatory and neuroinflammatory diseases, diabetes, especially pancreatic diabetes, neurodegenerative diseases, pain states, cancer as well as liver fibrosis and liver cirrhosis.
申请公布号 WO0125210(A3) 申请公布日期 2001.10.11
申请号 WO2000EP09153 申请日期 2000.09.19
申请人 BAYER AKTIENGESELLSCHAFT;ROSENTRETER, ULRICH;HENNING, ROLF;BAUSER, MARCUS;KRAEMER, THOMAS;VAUPEL, ANDREA;HUEBSCH, WALTER;DEMBOWSKY, KLAUS;SALCHER-SCHRAUFSTAETTER, OLGA;STASCH, JOHANNES-PETER;KRAHN, THOMAS;PERZBORN, ELISABETH 发明人 ROSENTRETER, ULRICH;HENNING, ROLF;BAUSER, MARCUS;KRAEMER, THOMAS;VAUPEL, ANDREA;HUEBSCH, WALTER;DEMBOWSKY, KLAUS;SALCHER-SCHRAUFSTAETTER, OLGA;STASCH, JOHANNES-PETER;KRAHN, THOMAS;PERZBORN, ELISABETH
分类号 A61K31/4418;A61K31/443;A61K31/4433;A61K31/4436;A61K31/4439;A61K31/444;A61K31/4545;A61K31/4709;A61K31/496;A61K31/5377;A61P1/16;A61P3/10;A61P9/10;A61P11/00;A61P13/00;A61P15/00;A61P25/00;A61P25/04;A61P29/00;A61P35/00;A61P43/00;C07D213/85;C07D401/12;C07D405/12;C07D409/12;C07D413/12;C07D417/12 主分类号 A61K31/4418
代理机构 代理人
主权项
地址