发明名称 HYDROXYPHENYL-PIPERAZINYL-METHYL-BENZAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN
摘要 Compounds of general formula (I), where R1 is selected from any one of pyridinyl, thienyl, furanyl, imidazolyl, and triazolyl; where each R1 heteroaromatic ring may optionally and independently be further substituted by 1, 2 or 3 substituents selected from straight and branched C1-C6 alkyl, NO2, CF3, C1-C6 alkoxy, chloro, fluoro, bromo, and iodo. The substitutions on the heteroaromatic ring may take place in any position on said ring systems; are disclosed and claimed in the present application, as well as separate enantiomers of the compounds and salts and pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in th e management of pain.
申请公布号 CA2402705(A1) 申请公布日期 2001.10.11
申请号 CA20012402705 申请日期 2001.03.30
申请人 ASTRAZENECA AB 发明人 BROWN, WILLIAM;PLOBECK, NIKLAS;WALPOLE, CHRISTOPHER
分类号 A61K31/341;A61K31/381;A61K31/4523;A61P1/00;A61P19/00;A61P25/00;A61P25/02;A61P25/04;C07D295/155;C07D307/52;C07D333/20;C07D401/06;C07D403/06;C07D405/06;C07D409/06;(IPC1-7):C07D401/06;A61K31/452 主分类号 A61K31/341
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