摘要 |
<p>Novel hydrazide derivatives represented by the following general formula (I). Because of having an excellent activity of inhibiting apo B-associated lipoprotein secretion, these hydrazide derivatives are useful as drugs for hyperlipemia, preferably cholesterol- or triglyceride-lowering agents wherein the ring A is an optionally substituted benzene or pyridine ring; Z1 represents lower alkylene; R1 to R3 may be the same or different and each represents H, hydrocarbyl, a heterocycle, etc.; R4 to R6 may be the same or different and each represents H, halogeno, hydrocarbyl, etc.; and R7 to R9 may be the same or different and each represents H, hydrocarbyl, etc.</p> |