TELOMERASE INHIBITOR POLYNUCLEOTIDES

摘要

Polynucleotide inhibitors and methods for inhibiting telomerase activity are provided. The polynucleotide inhibitors are substantially complementary to a portion of the human telomerase RNA component in a non-template region between nucleotide 137 and nucleotide 179 and contain certain modified nucleotide residues or certain modified linkages between adjacent nucleotides.