摘要 |
PROBLEM TO BE SOLVED: To improve the reaction operability and decrease the consumption of ammonium acetate in the production of 4-aminoquinoline or its derivative (e.g. 6-acetamido-4-aminoquinaldine) by the amination of 4-methoxyquinoline or its derivative (e.g. 6-acetamido-4-methoxyquinaldine) with ammonium acetate. SOLUTION: The above amination reaction is carried out in an amide solvent (e.g. dimethylformamide).
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