发明名称 METABOLIC PRODUCT OF HEXAHYDROPYRAZOLO[4,3-C]PYRIDINE
摘要 PROBLEM TO BE SOLVED: To provide a metabolic product of the compound of formula (I), its racemic-diastereomer mixture and optical isomer, its prodrug, a pharmaceutically permissible salt of the metabolic product, racemic-diastereomer mixture, optical isomer and prodrug, a pharmaceutical composition containing the above substance and a method for the treatment of diseases caused by the decrease of growth hormone level by the use of the metabolic product and the pharmaceutical composition. SOLUTION: The present invention relates to a kit containing the 1st unit agent containing a metabolic product of the compound of formula (I) and a pharmaceutically permissible carrier, excipient or diluent; the 2nd unit agent containing estrogen, Premarin(R), progesterone or a bisphosphonate compound (preferably alendronate) and a pharmaceutically permissible carrier, excipient or diluent; and a container.
申请公布号 JP2001278866(A) 申请公布日期 2001.10.10
申请号 JP20010066202 申请日期 2001.03.09
申请人 PFIZER PROD INC 发明人 KHOJASTEH-BAKHT SIAMAK CYRUS;O'DONNELL JOHN PAUL
分类号 C07D231/20;A61K31/4152;A61K31/437;A61P3/04;A61P5/00;A61P9/04;A61P17/02;A61P19/08;A61P19/10;A61P21/00;A61P35/00;A61P43/00;C07D471/04;C07K5/04;(IPC1-7):C07D231/20;A61K31/415 主分类号 C07D231/20
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