发明名称 METHOD OF PREVENTING ALLOGRAFT REJECTION
摘要 Disclosed is a use of a compound of the formula: (see fig. I) (wherein n is 1-3; A is O, S, CH2, NH or N-alkyl; B is CR4R5 where R4 and R5 are H, alkyl, R6R7-alkyl or R6R7-alkoxy in which R6 and R7 are H, alkyl, cycloalkyl, aryl or heteroaryl or R4 and R5 together with the C atom form cycloalkyl; R1 is tetrazolyl, carboxyl, carboxyalkenyl, alkyl cycloalkyl, etc. and R2 is H, F, Cl, alkyl, alkoxy, etc.), or a pharmaceutically acceptable salt thereof for suppressing the rejection of allogenic transplants in a mammal, including a human.
申请公布号 CA2218306(C) 申请公布日期 2001.10.09
申请号 CA19972218306 申请日期 1997.10.15
申请人 PFIZER INC. 发明人 SHOWELL, HENRY JAMES;WERINGER, ELORA JEANNE
分类号 C07D333/64;A61K31/35;A61K31/352;A61K31/353;A61K31/38;A61K31/381;A61K31/382;A61K31/41;A61K31/42;A61P37/06;C07D311/22;C07D311/36;C07D335/06;C07D337/08;C07D405/10;C07D413/10;(IPC1-7):A61K31/35;A61K31/33;A61K31/34;A61K31/40;A61K31/44;A61K31/55 主分类号 C07D333/64
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