SLM-1: a novel Sam68-like mammalian protein

摘要

The present invention relates to two Sam68-like mammalian proteins, namely SLM-1 and SLM-2, and nucleic acid molecules encoding them. The invention also relates to expression vectors and cells capable of expressing the proteins and antibodies capable of specifically binding to the proteins. Kits for the assay of tyrosine kinase activity are discussed which may be used to determine whether or not a cell is cancerous. The present invention further relates to transgenic animals such as "knockout mice". Knockout mice may be used to study the effect of test compounds on SLM-1 or SLM-2 deficiency.