| 摘要 |
For sakes of eliminating displacement zone and fully utilizing the void volume in traditional chromatography, a separation process herein disclosed is for better efficiency in separation of mixed solution of glucose and fructose into glucose and fructose solution. More specifically, the process implements a new mass transfer method onto an alkaline-earth metal cation exchanger bed for proceeding like SMB process, yet, in a single bed or multiple beds in a bundle with batch operation mode. Said new method further integrates with differential set-up protocols between solid phase resin and a multiplicity of liquid mixtures, an operation protocol to implement all above indicated methods. By the virtue of said new mass transfer method and differential set-up, the process herein disclosed is capable of separation of glucose and fructose feed solution into 100% yield of respective pure component. Said process is operated by sequential proceeding of feeding, fractions recovery, and enhancing concentration of separated fractions. The disclosed process cutbacks nearly 50% of resin stock compared with same throughput of SMB process having separation of 88% recovery of 90% fructose purity in product stream.
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