| 发明名称 |
Self-assembling polynucleotide delivery system |
| 摘要 |
This invention provides a self-assembling polynucleotide delivery system comprising components aiding in the delivery of the polynucleotide to the desired address which are associated via noncovalent interactions with the polynucleotide. The components of this system include DNA-masking components, cell recognition components, charge-neutralization and membrane-permeabilization components, and subcellular localization components. Specific compounds useful in this system are also provided.
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| 申请公布号 |
US6300317(B1) |
申请公布日期 |
2001.10.09 |
| 申请号 |
US19950469899 |
申请日期 |
1995.06.06 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
SZOKA, JR. FRANCIS C.;HAENSLER JEAN |
| 分类号 |
C12N15/09;A61K9/127;A61K31/70;A61K31/7125;A61K38/00;A61K47/48;A61K48/00;A61P11/00;A61P13/00;A61P19/00;A61P43/00;C07D401/14;C07F9/10;C07K7/66;C07K14/025;C08G83/00;C12N15/87;(IPC1-7):A61K48/00 |
主分类号 |
C12N15/09 |
| 代理机构 |
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