发明名称 |
Non-human animal model for growth deficiency and information processing or cognitive function defects and use thereof |
摘要 |
The present invention provides a non-human animal model, particularly a mouse model, for growth deficiency and information procesing or cognitive function defects, in which modified growth hormone is expressed. The modified growth hormone and nucleic acids coding therefor are also provided, as are the correspondingly modified recombinant mouse and human growth hormones. The invention further provides uses for the non-human animal model and the modified growth hormones, in particular for the modified human growth hormone in treating medical conditions associated with over-expression of growth hormone or IGF-1. |
申请公布号 |
AU6585501(A) |
申请公布日期 |
2001.10.08 |
申请号 |
AU20010065855 |
申请日期 |
2001.04.02 |
申请人 |
INGENIUM PHARMACEUTICALS AG |
发明人 |
EMMANUELLE CORNALI;MICHAEL CHRISTIAN NEHLS;VOLKER SCHLUTER;FRANK WATTLER;SIGRID WATTLER;STEFAN WOLF |
分类号 |
A01K67/027;A61K38/00;A61K48/00;C07K14/61;C12N15/85 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|