| 摘要 |
<p>Novel ubiquitin hydrolase-like polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length ubiquitin hydrolase-like proteins, the invention further provides isolated ubiquitin hydrolase-like fusion proteins, antigenic peptides, and anti-ubiquitin hydrolase-like antibodies. The invention also provides ubiquitin hydrolase-like nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a ubiquitin hydrolase-like gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.</p> |
