发明名称 |
ANTIPROGESTINS WITH PARTIAL AGONIST ACTIVITY |
摘要 |
The present invention features methods of inhibiting progestin activity in a cell or in a subject in need of such inhibition, and methods of treating or preventing progestin-dependent conditions in a subject in need of such treatment or prevention. The methods include administering an effective amou nt of a C-17-derivatized dexamethasone antiprogestin to the cell or the subject . The invention also provides methods of screening substances for progestin or antiprogestin activity, and methods of detecting progestins, progestin agonists, or antiprogestins in a sample, using the C-17-derivatized dexamethasone antiprogestins of the invention.
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申请公布号 |
CA2404172(A1) |
申请公布日期 |
2001.10.04 |
申请号 |
CA20012404172 |
申请日期 |
2001.03.23 |
申请人 |
GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, |
发明人 |
SIMONS, S. STONEY, JR. |
分类号 |
G01N33/53;A61K31/573;A61K31/585;A61P5/32;A61P7/06;A61P15/00;A61P15/04;A61P15/08;A61P15/18;A61P35/00;C07J5/00;C07J21/00;C12Q1/68;G01N33/74;(IPC1-7):A61K31/57 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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