发明名称 |
Novel receptor |
摘要 |
A receptor in substantially pure form obtainable from rat forebrain tissue which is characterized in that; a) compound A binds to it with a Kd of 40 nM for rat forebrain tissue, b) compound A binds to it with a Bmax of 220 pmol/g protein for rat forebrain tissue c) compound B binds to it with a Kd of 2 nM for rat forebrain tissue d) compound B binds to it with a Bmax of 220 pmol/g protein for rat forebrain tissue; and homologous receptors from other sources sharing at least 85% homology with the rat forebrain tissue.
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申请公布号 |
US2001027248(A1) |
申请公布日期 |
2001.10.04 |
申请号 |
US20010864618 |
申请日期 |
2001.05.24 |
申请人 |
SMITHKLINE BEECHAM P.L.C. |
发明人 |
HERDON HUGH JONATHAN;JERMAN JEFFREY CLIFFORD;CHAN WAI NGOR |
分类号 |
A61K38/00;C07B59/00;C07K14/705;(IPC1-7):A61K38/17 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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