发明名称 |
MONOOXYGENASE ASSAYS |
摘要 |
Cytochrome P-450 assay methods and kits for the methods are provided employing a cytochrome P-450 enzyme, substrates characterized by having an oxidizable methylene group oxidized to an aldehyde and a fluorescent hydrazine. A fluorescent hydrazine is added to the reaction mixture and the resulting hydrazone analyzed by capillary electrophoresis. The method finds use in evaluating compounds for enzyme modulating activity.
|
申请公布号 |
WO0173113(A2) |
申请公布日期 |
2001.10.04 |
申请号 |
WO2001US10155 |
申请日期 |
2001.03.29 |
申请人 |
ACLARA BIOSCIENCES, INC. |
发明人 |
SINGH, SHARAT;CHENNA, AHMED;SALIMI-MOOSARI, HOSSEIN;GIBBONS, IAN |
分类号 |
C12Q1/26;(IPC1-7):C12Q1/26 |
主分类号 |
C12Q1/26 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|