NON-HUMAN TRANSGENIC ANIMALS EXPRESSING PLATELET-DERIVED GROWTH FACTOR C (PDGF-C) AND USES THEREOF

摘要

Non-human transgenic animals overexpressing PDGF-C and cells thereof have be en created. The transgenic animals contain a nucleotide sequence that encodes f or platelet derived growth factor C (PDGF-C) or an analog thereof. These animal s are useful for studying disease states characterized by overexpression of PD GF- C, as well as useful for evaluating therapies intended to treat such disease s.