| 摘要 |
<p>A process for continuously producing an amide compound by reacting optionally processed cells of a nitrile hydratase-containing microorganism with a nitrile compound in an aqueous medium, characterized in that the optionally processed cells are brought into contact with the nitrile compound in the aqueous medium and the liquid reaction mixture thus obtained is further reacted under conditions having a plug-flow type part. By using this process, a high conversion ratio into a nitrile compound can be achieved and a nitrile compound solution having a high purity and a high concentration can be obtained without resort to any concentration step.</p> |
