| 摘要 |
The invention relates to a transdermal, therapeutical system of the matrix type. The inventive system comprises a backing layer that is impermeable to active agents, a detachable protective layer and a matrix that contains active agents on the basis of hydrophobic polymers. The active agent has a melting point above room temperature and is present in a concentration for at least part of the TTS application use, whereby said concentration exceeds the saturation solubility. The inventive system is characterised in that a polyacrylate polymer is admixed to the hydrophobic base polymers of the matrix of active agents and/or in that the matrix layer which contains the hydrophobic polymers is provided with a self-adhesive skin contact layer on the basis of polyacrylates.
|
