发明名称 |
Agent for the diagnosis and therapy of viral diseases |
摘要 |
Composition for treating viral diseases comprising a substance (I) that modifies the function of YB-1, is new. Independent claims are also included for the following: (1) a composition (a) for diagnosing viral diseases containing antibodies (Ab) directed against either YB-1 or P32; and (2) a composition (b) for diagnostic assessment of the risk of gene therapy with viral vectors containing Ab. - ACTIVITY : Antiviral. No biological data is provided. - MECHANISM OF ACTION : Reducing the concentration or activity of YB-1, a Y-box protein that controls gene expression in various viruses and enables replication of adenoviruses that are normally replication defective. |
申请公布号 |
AU5611701(A) |
申请公布日期 |
2001.10.03 |
申请号 |
AU20010056117 |
申请日期 |
2001.03.21 |
申请人 |
MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN |
发明人 |
HANS-DIETER ROYER;KARSTEN JURCHOTT;STEPHAN BERGMANN |
分类号 |
A61K38/00;A61K48/00;A61P31/12;C07K14/47;C12N15/113 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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