发明名称 |
3-substituted-4-pyrimidone derivatives |
摘要 |
3-Substituted-4-pyrimidone derivatives represented by formula (I) or salts thereof, solvates thereof or hydrates thereof, wherein R<1> represents a C1-C18 alkyl group which may be substituted or a C6-C14 aryl group which may be substituted; R<2> represents a C1-C18 alkyl group which may be substituted or a C7-C20 aralkyl group which may be substituted; and a medicament comprising said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a disease caused by tau protein kinase 1 hyperactivity such as neurodegenerative diseases (e.g. Alzheimer disease) and the like. |
申请公布号 |
AU4277201(A) |
申请公布日期 |
2001.10.03 |
申请号 |
AU20010042772 |
申请日期 |
2001.03.23 |
申请人 |
MITSUBISHI-TOKYO PHARMACEUTICALS, INC.;SANOFI-SYNTHELABO |
发明人 |
RYOICHI ANDO;FUMIAKI UEHARA;KENICHI SAITO |
分类号 |
A61K31/506;A61P9/10;A61P25/00;A61P25/16;A61P25/28;A61P43/00;C07D401/04 |
主分类号 |
A61K31/506 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|