发明名称 Stable drug composition
摘要 A stabilized pharmaceutical composition comprising (R)-2-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-spiro-3'-pyrrolidine-1,2',3,5'-tetrone (hereinafter, referred to as "AS-3201") and as a stabilizer at least one acidic substance having an acidity more potent than that of AS-3201, such as ascorbic acid, citric acid, tartaric acid, lactic acid, maleic acid, malic acid or phosphoric acid.
申请公布号 US6297244(B1) 申请公布日期 2001.10.02
申请号 US20000529719 申请日期 2000.04.19
申请人 DAINIPPON PHARMACEUTICAL CO., LTD. 发明人 OHASHI MAMORU;OGASAWARA KAZUYOSHI;SHIRAI YOSHIMI;FUJIOKA HIROSHI
分类号 A61K31/499;A61K47/12;(IPC1-7):A61K31/50 主分类号 A61K31/499
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