发明名称 |
Recombinant cephalosporin C amidohydrolase in cephalosporin biosynthesis |
摘要 |
The present invention relates to an enzyme process for the one-step conversion of cephalosporin C or a derivative thereof into 7-aminocephalosporanic acid or a corresponding derivative thereof. The one step conversion is effected using a cephalosphorin C amidohydrolase derived from Pseudomonas Vesicularis B965, or from any cephalosporin C amidolydrolase producing or potentially producing descendants thereof, or from expression of DNA derived from Pseudomonas Vesicularis B965 or any cephalosporin C amidohydrolase producing or potentially producing descendants thereof.
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申请公布号 |
US6297032(B1) |
申请公布日期 |
2001.10.02 |
申请号 |
US19990236645 |
申请日期 |
1999.01.26 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
RAMSDEN MARTIN;SPENCE DAVID WILSON |
分类号 |
C12N15/09;C12N1/21;C12N9/80;C12N15/00;C12N15/55;C12P35/02;C12R1/19;C12R1/38;(IPC1-7):C12N9/14;C12N1/20;C07H21/04;C12P35/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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地址 |
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