发明名称 Cyanoaziridines for treating cancer
摘要 The present invention is directed to novel anti-cancer compounds of the formula.whereinX is CN,R4 is hydrogen or lower alkyl; andR5 is lower alkyl, lower cycloalkyl, alkenyl, alkynyl, aryl, monosubstituted aryl, disubstituted aryl, aryl lower alkyl, lower alkoxycarbonyl lower alkyl, or heterocyclic ring, with the proviso that when X is CN, and R4 is hydrogen, then R5 is not CH3, C6H5, or, p-nitrophenyl.R4, R5 and N taken together form a heterocyclic ring.
申请公布号 US6297230(B1) 申请公布日期 2001.10.02
申请号 US20000446652 申请日期 2000.04.10
申请人 AMPLIMED, INC. 发明人 REMERS WILLIAM A.;HERSH EVAN M.;DORR ROBERT T.;IYENGAR BHASHYAM
分类号 C07D203/20;C07D401/12;(IPC1-7):A61K31/396;C07C255/46;C07D203/12 主分类号 C07D203/20
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