| 摘要 |
PROBLEM TO BE SOLVED: To obtain a new compound having excellent calcium antagonism, in particular neuroselective calcium antagonism. SOLUTION: This new compound is represented by the formula [Ar is a (substituted) 5- to 14-membered aromatic cyclic group, or the like; ring A is either one ring selected from piperazine, homopiperazine and piperidine rings, and the like; ring B is a (substituted) 3-14C hydrocarbon ring, or the like; E is a single bond, a group of the formula CO, or the like; X is a single bond, oxygen atom, or the like; R1 is H, a halogen atom, OH, or the like; and D1, D2, W1 and W2 are each a single bond or a (substituted) 1-6C alkylene chain]. This new compound may assume a salt or hydrate form. |
