| 发明名称 |
HETEROARYL SUCCINAMIDES AND THEIR USE AS METALLOPROTEINASE INHIBITORS |
| 摘要 |
The present invention is directed to compound of formula (I), wherein R1, R2, R3, R4, R5, X, Y and (la) are as defined herein. These compounds are useful for inhibiting the activity of a metalloproteinase by contacting the metalloproteinase with an effective amount of the inventive compounds. |
| 申请公布号 |
YU20199(A) |
申请公布日期 |
2001.09.28 |
| 申请号 |
YU19990000201 |
申请日期 |
1997.10.06 |
| 申请人 |
AGOURON PHARMACEUTICALS INC.;SYNTEX (U.S.A.) INC. |
发明人 |
BENDER, STEVEN L.;CASTELHANO, ARLINDO L.;CHONG, WESLEY K.M.;ABREO, MELWYN A.;BILLEDEAU, ROLAND J.;CHEN, JIAN JEFFREY;DEAL, JUDITH G. |
| 分类号 |
C07D233/58;A61K31/00;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/40;A61K31/4025;A61K31/407;A61K31/415;A61K31/4164;A61K31/4178;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4436;A61K31/4439;A61K31/55;A61K38/00;A61P1/00;A61P1/02;A61P9/00;A61P9/10;A61P19/00;A61P19/02;A61P19/10;A61P29/00;A61P35/00;A61P43/00;C07D207/32;C07D207/327;C07D207/337;C07D231/12;C07D233/54;C07D233/56;C07D307/54;C07D333/24;C07D333/26;C07D401/04;C07D401/10;C07D401/12;C07D401/14;C07D403/12;C07D405/10;C07D405/12;C07D405/14;C07D409/12;C07D487/04;C07D487/08;C07D498/08;C07D521/00;C07K5/072 |
主分类号 |
C07D233/58 |
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