| 发明名称 |
(R)-5-BROMO-N-(1-ETHYL-4-METHYLHEXAHYDRO-1H-1,4-DIAZEPIN-6-YL)-2-METHOXY-6-METHYLAMINO-3-PYRIDINE-CARBOXAMIDE, PROCESS FOR PRODUCING THE SAME AND MEDICINAL COMPOSITION CONTAINING THE SAME |
| 摘要 |
<p>This invention discloses a compound which is expressed by formula (I) below: <CHEM> or physiologically acceptable acid addition salts thereof. The claimed compound exhibits excellent antiemetic effect based on its potent serotonin S3 and dopamine D2 receptor antagonistic activities, and is useful for treatment or prophylaxis of various gastrointestinal symptoms which are associated with various diseases and drug administration.</p> |
| 申请公布号 |
GR3036089(T3) |
申请公布日期 |
2001.09.28 |
| 申请号 |
GR20010400934T |
申请日期 |
2001.06.19 |
| 申请人 |
DAINIPPON PHARMACEUTICAL CO., LTD. |
发明人 |
KATO, SHIRO;HIROKAWA, YOSHIMI;MORIE, TOSHIYA;HARADA, HIROSHI;YOSHIDA, NAOYUKI |
| 分类号 |
A61K31/44;A61K31/5513;A61P1/08;C07D243/08;C07D401/12;(IPC1-7):C07D401/12;A61K31/55 |
主分类号 |
A61K31/44 |
| 代理机构 |
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