发明名称 IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 A novel imidazole derivatives of formula I: <CHEM> wherein R<1> is hydrogen, alkyl, halogen, or optionally substituted aryl; R<2> is alkyl, optionally substituted aryl optionally substituted aralkyl, or optionally substituted hetero ring group; R<3> is hydrogen, alkyl, optionally substituted aryl, optionally substituted aralkyl, or optionally substituted hydroxyalkyl; R<4> is hydrogen, alkyl, halogen, acyl, optionally substituted hydroxyalkyl, optionally esterified or amidated carboxyl group, hydroxy group, aryl or arylthio; X is S, SO, SO2, CH2, or Se; n is an integer of 1 to 3, or a pharmaceutically acceptable salt thereof, said derivative having anti-HIV activity and being useful for the treatment of HIV infections.
申请公布号 HU219917(B) 申请公布日期 2001.09.28
申请号 HU19930000107 申请日期 1993.01.15
申请人 SHIONOGI AND CO. LTD. 发明人 FUJIWARA TAMIO;MATSUMOTO HIROSHI;OGATA MASARU;SATO AKIHIKO;SUGIMOTO HIROHIKO;SUGITA KEN-ICHI
分类号 A61K31/415;A61K31/44;A61K31/4427;A61P31/12;C07D233/54;C07D233/60;C07D233/64;C07D233/70;C07D233/80;C07D233/84;C07D233/86;C07D233/90;C07D401/06;C07D403/06;C07D413/06;C07D417/06 主分类号 A61K31/415
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