发明名称 |
Composition comprising ciclesonide, propellant (1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoropropane or a mixture thereof) and ethanol |
摘要 |
The pharmaceutical composition comprises a therapeutically effective amount of a compound of formula (I), in which: R1 is 1-butyl, 2-butyl, cyclohexyl or phenyl and R2 is acetyl or isobutanoyl, and a propellant selected from 1,1,1,2-tetrafluoroethane, 1,1,1,2,3,3,3-heptafluoropropane and a mixture thereof, and ethanol in an amount effective to solubilise the compound of formula (I) and optionally a surfactant. Also described is a pharmaceutical composition comprising the compound of formula (I), a hydrofluorocarbon propellant and a co-solvent in an amount effective to solubilise the compound of formula (I); in the form of an aerosol and contained in an aerosol canister equipped with a dispensing valve.
|
申请公布号 |
NZ500874(A) |
申请公布日期 |
2001.09.28 |
申请号 |
NZ19980500874 |
申请日期 |
1998.05.18 |
申请人 |
MINNESOTA MINING AND MANUFACTURING COMPANY |
发明人 |
SCOTT, JOHN S;MULLER, HELGERT;FATANIA, KANU M;OLIVER, MARTIN J |
分类号 |
A61K9/00;A61K9/12;A61K31/573;A61K31/58;A61K47/06;A61K47/10;A61P11/06;A61P29/00;C07J71/00;(IPC1-7):A61K9/08 |
主分类号 |
A61K9/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|