发明名称 |
HUMAN PARIS-1 ANTIGEN AND NUCLEIC ACIDS: DIAGNOSTIC AND THERAPEUTIC USES |
摘要 |
The present invention relates to the discovery, identification and characterization of a novel tumor suppressor gene designated PARIS-1. The invention includes nucleotide sequences of the PARIS-1 gene and amino acid sequences of its encoded protein product(s), as well as fragments, derivatives and analogs thereof. The invention also includes the production of PARIS-1 proteins, fragments and derivatives and of antibodies specific for PARIS-1 gene products. The invention further comprises agents and compositions which can modulate the expression of PARIS-1 or PARIS-1 expression products to effect the proliferation of cells which express PARIS-1. One particular embodiment comprises agents and compounds which can slow or ablate the proliferation of prostate tumor cells.
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申请公布号 |
WO0170244(A1) |
申请公布日期 |
2001.09.27 |
申请号 |
WO2001US08083 |
申请日期 |
2001.03.13 |
申请人 |
NORTHWEST BIOTHERAPEUTICS, INC.;ZHOU, YALING |
发明人 |
ZHOU, YALING |
分类号 |
A61K38/00;A61K39/00;A61K48/00;A61P35/00;C07K14/47;(IPC1-7):A61K35/12;A61K38/04;A61K39/395;C07H21/04;C07K5/00;C07K5/04;C07K7/02;C07K14/00;C07K16/00;C07K16/18;C12N15/09;C12N15/63 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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