发明名称 SULFUR SUBSTITUTED ARYLDIFLUOROMETHYLPHOSPHONIC ACIDS AS PTP-1B INHIBITORS
摘要 The invention encompasses the novel class of compounds represented by formula (I), which are inhibitors of the PTP-1B enzyme . The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes.
申请公布号 WO0170753(A1) 申请公布日期 2001.09.27
申请号 WO2001CA00373 申请日期 2001.03.21
申请人 MERCK FROSST CANADA & CO.;LI, CHUN, SING;LAU, CHEUK, K.;THERIEN, MICHEL;GAUTHIER, JACQUES, Y.;BAYLY, CHRISTOPHER;DUFRESNE, CLAUDE;FORTIN, REJEAN;LEBLANC, YVES;ROY, PATRICK;WANG, ZHAOYIN 发明人 LI, CHUN, SING;LAU, CHEUK, K.;THERIEN, MICHEL;GAUTHIER, JACQUES, Y.;BAYLY, CHRISTOPHER;DUFRESNE, CLAUDE;FORTIN, REJEAN;LEBLANC, YVES;ROY, PATRICK;WANG, ZHAOYIN
分类号 A61K45/00;A61K31/10;A61K31/137;A61K31/365;A61K31/437;A61K31/4406;A61K31/455;A61K31/64;A61K31/66;A61K31/662;A61K31/663;A61K38/28;A61K45/06;A61P1/00;A61P1/04;A61P1/18;A61P3/04;A61P3/06;A61P3/10;A61P5/48;A61P9/08;A61P9/10;A61P25/00;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07F9/38;C07F9/40;C07F9/553;C07F9/572;C07F9/576;C07F9/58;C07F9/59;C07F9/60;C07F9/6506;C07F9/6512;C07F9/6518;C07F9/6524;C07F9/653;C07F9/6539;C07F9/655;C07F9/6558;(IPC1-7):C07F9/38 主分类号 A61K45/00
代理机构 代理人
主权项
地址