| 发明名称 |
MATRICES CONTAINING NITRIC OXIDE DONORS AND REDUCING AGENTS AND THEIR USE |
| 摘要 |
A composition comprises a hydrophobic matrix, a reducible nitric oxide (NO) donor, and an intrinsic reductant reactably associated together with the reducible NO donor within the matrix, and releases an effective amount of NO from the matrix when wetted at physiological pH, independently of the presence or absence of extrinsic reducing agents. The composition inhibits the growth of target cells in a target medium.
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| 申请公布号 |
WO0170199(A1) |
申请公布日期 |
2001.09.27 |
| 申请号 |
WO2001US08806 |
申请日期 |
2001.03.20 |
| 申请人 |
NOVOVASCULAR, INC.;ZHAO, YI-JU;BRAATZ, JAMES, A.;ROSEN, GERALD, M. |
发明人 |
ZHAO, YI-JU;BRAATZ, JAMES, A.;ROSEN, GERALD, M. |
| 分类号 |
A61K9/00;A61K9/20;A61K31/198;A61K31/295;A61K31/375;A61K33/00;A61K33/26;A61K33/42;A61K35/14;A61K47/34;A61L27/00;A61L27/34;A61L27/54;A61L29/08;A61L29/16;A61L31/10;A61L31/16;A61L33/00;A61P1/00;A61P7/02;A61P9/00;A61P9/08;A61P15/00;A61P15/10;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P35/00;A61P37/04;A61P43/00;(IPC1-7):A61K9/14;A01N59/26;A01N59/24;C08K3/28 |
主分类号 |
A61K9/00 |
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