LIPOXIN ANALOGS AND METHODS FOR THE TREATMENT OF PERIODONTAL DISEASE

摘要

This invention provides new lipoxin analogs, compositions containingthese analogs, and methods of using these compounds and compositionsfor treating and preventing oral inflammation, including gingivitis,periodontitis, and other forms of periodontal disease. The invention also provides for methods of treating and preventing oral inflammation,including gingivitis, periodontitis, and other forms of periodontal disease with compositions containing COX-2 inhibitors. Further, the invention provides methods for preventing systemic diseases beyond theoral cavity that are related to periodontal disease using the compositions containing lipoxin analogs, COX-2 inhibitors, or both.