发明名称 |
Photocleavable and acid cleavable linkers for combinatorial chemistry |
摘要 |
A substrate for solid phase synthesis comprising a solid phase-linker combination of the formula I is disclosed. Also disclosed are processes for preparing the substrate and chemical intermediates useful therein. Among the novel intermediates are compounds of the formula II wherein R1 is -NO2 or -CHO; R2 is -OCH3, -CHO or -H; R3 is chosen from the group consisting of hydroxyl, the residue of a solid support having a plurality of amino groups, and the residue of an ester, and n=1 or 3-12. A substrate of solid phase synthesis of the formula III is also disclosed. |
申请公布号 |
US2001025084(A1) |
申请公布日期 |
2001.09.27 |
申请号 |
US20010766987 |
申请日期 |
2001.01.22 |
申请人 |
TRAN VINH D.;MA VU VAN;LIU RUIYAN |
发明人 |
TRAN VINH D.;MA VU VAN;LIU RUIYAN |
分类号 |
C07B61/00;C07C59/74;C07C205/37;C07C205/44;C07C235/06;C08F8/28;C08F8/30;(IPC1-7):C07C205/00;C07C309/00;C07C62/36;C07C62/32;C07C62/38;G01N33/53;C08L29/02 |
主分类号 |
C07B61/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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