发明名称 |
NOVEL TRYPSIN FAMILY SERINE PROTEASES |
摘要 |
<p>Two novel trypsin-family serine proteases specifically expressed in adult mouse testis ("Tespec PRO-1" and "Tespec PRO-2"), and a novel trypsin-family serine protease derived from mouse ("Tespec PRO-3") have been isolated. Also, two novel trypsin-family serine proteases derived from human ("Tespec PRO-2" and "Tespec PRO-3") have been isolated. It has been suggested that these proteins are involved in sperm differentiation and maturation, and sperm functions (e.g., fertilization). Therefore, these proteins are useful for development of novel therapeutics and diagnostics for infertility, as well as for development of novel contraceptives.</p> |
申请公布号 |
EP1136548(A1) |
申请公布日期 |
2001.09.26 |
申请号 |
EP19990951213 |
申请日期 |
1999.11.02 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
SENOO, CHIAKI;NUMATA, MARIKO |
分类号 |
C12N9/64;A61K38/00;C07K16/40;C12N5/10;C12N15/57;C12P21/02;C12P21/08;C12Q1/37;G01N33/573;(IPC1-7):C12N9/64 |
主分类号 |
C12N9/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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