发明名称 |
1-[(1-Substituted-4-piperidinyl)methyl]-4-piperidine derivative, process for producing the same, medicinal compositions containing the same and intermediates of these compounds |
摘要 |
Compound of the formula (I):wherein Ar is a group of the following formula (Ar-1) or (Ar-2):A is a group of the formula:oror a pharmaceutically acceptable acid addition salt thereof, a process for preparing the same, a pharmaceutical composition containing the same, and intermediates therefor. The compounds of the present invention show a potent affinity for 5-HT4 receptors, and they are useful as a gastrointestinal motility enhancer or a gastrointestinal prokinetic agent.
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申请公布号 |
US6294555(B1) |
申请公布日期 |
2001.09.25 |
申请号 |
US20000674162 |
申请日期 |
2000.10.27 |
申请人 |
DAINIPPON PHARMACEUTICAL CO., LTD. |
发明人 |
KATO SHIRO;TOYOTOMI YOSHIHITO;TATEISHI HIROTAKE;HARADA HIROSHI;YOSHIDA NAOYUKI;MORIKAGE KAZUO;MORIKAGE YUKIKO |
分类号 |
A61K31/445;A61K31/495;A61K31/535;A61K31/54;A61P1/00;C07D211/58;C07D211/96;C07D405/12;C07D405/14;(IPC1-7):A61K31/445;C07D401/06 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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