发明名称 Material for passage through the blood-brain barrier
摘要 A material which has the ability to effect it's passage, at least in part, and the ability to transport other materials through the blood-brain barrier which includes any one or more pure sugars or pure amino sugars from the group consisting of meso ethritol, zylitol, D(+) galactose, D(+) lactose, D(+) xylose, dulcitol, myo-insoitol, L(-) fructose, D(-) mannitol, sorbitol, D(+) glucose, D(+) arabinose, D(-) arabinose, celloboise, D(+) maltose, D(+) raffinose, L(+)rhamnose, D(+) melibiose, D(-) ribose, adonitol, D(+) arabitol, L(-) arabitol, D(+) fucose, L(-) fucose, D(-) lyxose, L(+) lyxose, L(-) lyxose, D(+) glucosamine, D mannosamine, and D galactosamine; and any one or more amino acids from the group consisting of arginine, asparagine, aspartic acid, cysteine, glutamic acid, glycine, histidine, leucine, methionine, phenylalanine, proline, serine, threonine, glutamine, lysine, tryptophan, tyrosine, valine, and taurine. For use in the research or treatment of a subject that material is combined with one or more of the substances beta carotene, xanthophyll, lecithin, calcium, somatostatin, vasopressin, endorphin, enkephalin, acetyl-L-carnitine, GABA, dynorphin, L-tryptophan, choline, thiamine, pyridoxine, niacin, L-arginine, hydroxyproline, NGF, methionine, cystine, potassium, phosphorus, chlorine, sodium, vitamins A, B, C, D and E, and selenium.
申请公布号 US6294520(B1) 申请公布日期 2001.09.25
申请号 US19890341487 申请日期 1989.03.27
申请人 NAITO ALBERT T. 发明人 NAITO ALBERT T.
分类号 A61K8/44;A61K8/60;A61K31/14;A61K31/185;A61K31/198;A61K31/40;A61K31/405;A61K31/4172;A61K31/455;A61K31/685;A61K31/70;A61K31/7004;A61K31/7008;A61K31/7016;A61K45/06;A61Q7/00;A61Q19/08;(IPC1-7):A61K31/435 主分类号 A61K8/44
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