发明名称 |
Methods of preventing and treating respiratory viral infeciton using immunomodulatory polynucleotide sequences |
摘要 |
The invention provides methods of preventing and/or treating infection by a respiratory virus such as respiratory syncytial virus (RSV) and SARS-associated coronavirus, particularly reducing infection and/or one or more symptoms of respiratory virus infection. A polynucleotide comprising an immunostimulatory sequence (an "ISS") is administered to an individual which is at risk of being exposed to a respiratory virus, has been exposed to a respiratory virus or is infected with a respiratory virus. The ISS is administered without any antigens of the respiratory virus. Administration of the ISS results in reduced incidence and/or severity of one or more symptoms of respiratory virus infection. |
申请公布号 |
AU4358701(A) |
申请公布日期 |
2001.09.24 |
申请号 |
AU20010043587 |
申请日期 |
2001.03.12 |
申请人 |
DYNAVAX TECHNOLOGIES CORPORATION |
发明人 |
GARY VAN NEST |
分类号 |
C12N15/09;A61K31/7105;A61K31/711;A61K31/7115;A61K39/39;A61K48/00;A61P31/14;A61P31/16 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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