发明名称 |
Biokonversioner, der katalyseres af toluen-monooxygenasen fra Pseudomonas mendocina-KR-1 |
摘要 |
Disclosed and claimed are toluene monooxygenase (TMO) gene sequences from Pseudomonas mendocina KR-1, TMO proteins encoded by these sequences, recombinant plasmids containing such sequences, and microorganism host cells containing such plasmids. A five-gene and six-gene TMO gene cluster encode proteins that are useful in a variety of bioconversions. In particular, the TMO gene cluster is useful for the preparation of p-hydroxyphenylacetic acid and indigo. In addition, the TMO gene cluster is useful for the degradative bioconversion of toxic compounds, such as trichloroethylene. |
申请公布号 |
DK0504349(T3) |
申请公布日期 |
2001.09.24 |
申请号 |
DK19910917156T |
申请日期 |
1991.08.21 |
申请人 |
AMGEN INC. |
发明人 |
YEN, KWANG-MU;BLATT, LAWRENCE, M.;KARL, MICHAEL, R. |
分类号 |
C07K14/195;C07K14/00;C07K14/41;C12N;C12N1/21;C12N9/02;C12N15/09;C12N15/52;C12N15/53;C12N15/63;C12N15/78;C12P7/22;C12P7/42;C12P17/10;C12R1/19;C12R1/38 |
主分类号 |
C07K14/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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